Techniques used for the discovery of therapeutic compounds: The case of SARS
Identifieur interne : 003C77 ( Main/Exploration ); précédent : 003C76; suivant : 003C78Techniques used for the discovery of therapeutic compounds: The case of SARS
Auteurs : Shuai Chen [République populaire de Chine] ; Lili Chen [République populaire de Chine] ; Kaixian Chen [République populaire de Chine] ; Xu Shen [République populaire de Chine] ; Hualiang Jiang [République populaire de Chine]Source :
- Drug Discovery Today. Technologies [ 1740-6749 ] ; 2006.
Abstract
Severe acute respiratory syndrome coronavirus (SARS-CoV) is the etiological agent of SARS disease, which has ever severely menaced humans from the end of 2002 to June 2003. To date, great efforts have been made for the discovery of therapeutic compounds by using various technologies. In this report, we present a survey of these techniques and their applications in the development of promising anti-SARS agents.
Url:
DOI: 10.1016/j.ddtec.2006.09.005
PubMed: 24980529
PubMed Central: 7105914
Affiliations:
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Anand</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jenkins, J L" uniqKey="Jenkins J">J.L. Jenkins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smith, A" uniqKey="Smith A">A. Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kraemer, O" uniqKey="Kraemer O">O. Kraemer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lyne, P D" uniqKey="Lyne P">P.D. Lyne</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xiong, B" uniqKey="Xiong B">B. Xiong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, H" uniqKey="Yang H">H. Yang</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Liu, Z" uniqKey="Liu Z">Z. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rajnarayanan, R V" uniqKey="Rajnarayanan R">R.V. Rajnarayanan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, L" uniqKey="Chen L">L. Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dooley, A J" uniqKey="Dooley A">A.J. Dooley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sun, H" uniqKey="Sun H">H. Sun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, J H" uniqKey="Lu J">J.H. Lu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fan, K" uniqKey="Fan K">K. Fan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, C W" uniqKey="Lin C">C.W. Lin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bacha, U" uniqKey="Bacha U">U. Bacha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jain, R P" uniqKey="Jain R">R.P. Jain</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuo, C J" uniqKey="Kuo C">C.J. Kuo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, C N" uniqKey="Chen C">C.N. Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Blanchard, J E" uniqKey="Blanchard J">J.E. Blanchard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsu, J T" uniqKey="Hsu J">J.T. Hsu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsu, W C" uniqKey="Hsu W">W.C. Hsu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shie, J J" uniqKey="Shie J">J.J. Shie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chou, C Y" uniqKey="Chou C">C.Y. Chou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuang, W F" uniqKey="Kuang W">W.F. Kuang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, C Y" uniqKey="Wu C">C.Y. Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kao, R Y" uniqKey="Kao R">R.Y. Kao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shie, J J" uniqKey="Shie J">J.J. Shie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sittampalam, G S" uniqKey="Sittampalam G">G.S. Sittampalam</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, C W" uniqKey="Lin C">C.W. Lin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cooper, M A" uniqKey="Cooper M">M.A. Cooper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fagerstam, L G" uniqKey="Fagerstam L">L.G. Fagerstam</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Markgren, P O" uniqKey="Markgren P">P.O. Markgren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sinchaikul, S" uniqKey="Sinchaikul S">S. Sinchaikul</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ding, L" uniqKey="Ding L">L. Ding</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Silverman, L" uniqKey="Silverman L">L. Silverman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Joubert, P" uniqKey="Joubert P">P. Joubert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Han, Y S" uniqKey="Han Y">Y.S. Han</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ratia, K" uniqKey="Ratia K">K. Ratia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, A" uniqKey="Cheng A">A. Cheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, S K" uniqKey="Wong S">S.K. Wong</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Chen, Shuai" sort="Chen, Shuai" uniqKey="Chen S" first="Shuai" last="Chen">Shuai Chen</name></noRegion><name sortKey="Chen, Kaixian" sort="Chen, Kaixian" uniqKey="Chen K" first="Kaixian" last="Chen">Kaixian Chen</name><name sortKey="Chen, Lili" sort="Chen, Lili" uniqKey="Chen L" first="Lili" last="Chen">Lili Chen</name><name sortKey="Jiang, Hualiang" sort="Jiang, Hualiang" uniqKey="Jiang H" first="Hualiang" last="Jiang">Hualiang Jiang</name><name sortKey="Jiang, Hualiang" sort="Jiang, Hualiang" uniqKey="Jiang H" first="Hualiang" last="Jiang">Hualiang Jiang</name><name sortKey="Shen, Xu" sort="Shen, Xu" uniqKey="Shen X" first="Xu" last="Shen">Xu Shen</name><name sortKey="Shen, Xu" sort="Shen, Xu" uniqKey="Shen X" first="Xu" last="Shen">Xu Shen</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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